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The potential concern is that excessive NMN supplementation might lead to a decrease in the body's available methyl groups, which play crucial roles in various biological processes including DNA methylation and neurotransmitter synthesis. | The potential concern is that excessive NMN supplementation might lead to a decrease in the body's available methyl groups, which play crucial roles in various biological processes including DNA methylation and neurotransmitter synthesis. | ||
For that reason, some individuals who take NMN also supplement with Trimethylglycine (TMG), a methyl donor, to ensure that they are not depleting their body's methyl groups. However, this is a precautionary measure and not necessarily based on concrete evidence. | For that reason, some individuals who take NMN also supplement with [[Trimethylglycine (TMG)]], a [[Methyl Donors|methyl donor]], to ensure that they are not depleting their body's methyl groups. However, this is a precautionary measure and not necessarily based on concrete evidence. | ||
However, there are a few important points to consider: | However, there are a few important points to consider: | ||