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Nicotinamide Mononucleotide (NMN): Difference between revisions

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* oral admission at 9 AM
* oral admission at 9 AM
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* 10 men
* 10 healthy men
* 40-60 years
* 40-60 years
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* Admission was safe and well-tolerated in healthy men
* admission was safe and well-tolerated
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|Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550608/</ref>
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* randomized, placebo-controlled, double-blind
* 10-week
* 250 mg/day
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* 25 postmenopausal women with prediabetes
* overweight or obese (BMI 25.3 - 39.1)
* 56 - 66 years
* 12 placebo, 13 NMN group
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* increase in skeletal muscle insulin signaling, insulin sensitivity, and muscle remodeling
* improvement in muscle insulin sensitivity is clinically relevant and is similar to the improvement observed after ~10% weight loss
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